Peptide Synthesis and Applications by John Howl

Synopsis

This collection introduces the common techniques of solid phase peptide synthesis and describes the preparation of materials ranging from small peptides to proteins. Topics of the 15 chapters include modification of peptides and other drugs using lipoamino acids and sugars, synthesis of cell-penetrating peptides for cargo delivery, expressed protein ligation for protein semi-synthesis and engineering, quenched fluorescent substrate-based peptidase assays, cyclic peptide libraries, and peptide bioconjugates. The protocols list the equipment and reagents needed and provide step-by-step instructions for each method. Annotation ©2004 Book News, Inc., Portland, OR