Ecto-Atpases: Recent Progress on Structure and Function by Liselotte Plesner, Terence L. Kirley (Editor), Aileen F. Knowles (Editor)

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Distribution of different ATP-diphosphohydrolase isoforms, etc.

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Forty-one papers and three discussion sessions from the August 1996 workshop which premiered the results of the molecular cloning of potato apyrase showing five E-type ATPases from plants and microorganisms share consensus sequences found in human and murine CD39. The contributors demonstrated the ubiquitous nature of the ecto-ATPases presenting reports of the enzyme from a variety of organisms and tissues, a consensus was reached that E-type ATPases from organisms throughout the phylogenetic tree are related, and clear evidence was demonstrated of the important roles of ecto-ATPases in thromboregulation, transplant rejection, and parasitic survival as well as their role in lymphocyte function and clinically relevant areas such as hearing, kidney, epilepsy, and cancer. Annotation c. by Book News, Inc., Portland, Or.