From Barnes & Noble

The Barnes & Noble Review

When The Breast Cancer Prevention Diet by Dr. Bob Arnot, the chief medical correspondent for NBC, came out, it was met with both controversy and eager acceptance, and it hit the No. 1 slot on both the New York Times and Wall Street Journal bestseller lists. Even though subsequent research did not exactly prove that proper nutrition can prevent or cure cancer, there is good evidence to suggest that it plays a role, evidence the public is obviously eager to embrace. Now Arnot takes that same research, as well as the personal experiences of himself and other men, and applies it to the prevention, control, and cure of prostate cancer.

One of the key findings that Arnot uses to suggest that nutrition can help prevent prostate cancer is the incidence of the disease among certain ethnic groups. China and other Asian countries have the lowest rate of incidence; African Americans have the highest rate of anyone in the world. Although there are other factors that may play into these incident rates, nutrition is certainly high on the list, and Arnot devotes the first section of the book to reviewing this evidence in an effort to support his theory that prostate cancer is largely a nutritional disease.

The second section deals with the nutritional recommendations that Arnot feels will enhance one's ability to avoid prostate cancer or, if the disease has already struck, help contain it. Chief among the nutritional wonders in Arnot's diet is soy: soy beans, soy nuts, soy milk, tofu, tempeh...if it's made from soy, Arnot has it in this book. According to Arnot, the key to soy's importance is a high concentration of genistein, a plant hormone that appears to inhibit the growth of new blood vessels (which are necessary for tumor growth) and slow the cycle of prostate cancer cells. As a side benefit, soy also contains tyrosine, an amino acid that enhances one's alertness.

Arnot also looks into other dietary factors that play a role, promoting antioxidant-rich vegetables and fruits, explaining how different types of fats factor into the equation, mentioning the exciting new findings surrounding lycopene, and discussing the problems related to foods with a high glycemic index, which can cause insulin resistance and weight problems. He provides sample diets, a number of recipes, and guidelines for selecting foods when eating out. There are also several charts that list various values for foods.

The third section of the book deals with lifestyle changes, such as adopting a long-term diet, dealing with stress using relaxation and meditation techniques, and implementing an exercise regimen. There are certain correlations between heart disease and prostate cancer, and Arnot's diet and lifestyle changes will aid in the prevention of both. And because the diet is essentially the same as the one Arnot advocates for preventing breast cancer (the one exception being the amount of calcium recommended) there is added incentive for couples to adopt these lifestyle changes together, which may make compliance a little easier.

In the final sections of the book, Arnot provides an overview of the preventive, diagnostic, and treatment tools available for prostate cancer. Chief among these is the PSA test, a relatively simple blood test that can indicate the presence of prostate cancer even before any physical signs appear. Chemotherapy, radiation therapy, and surgical interventions are all reviewed, and the pros and cons of each are weighed. Several men, all of whom have been diagnosed with prostate cancer -- a few of them with cases so severe they were given only months to live -- provide their stories. They review their diagnoses, the dietary and other lifestyle changes they made as a result, and the successes they have achieved since. Although there is no way to know how many men have taken the same steps and made the same changes with little or no success, these anecdotes serve their purpose -- they are very encouraging and appear, at least on the surface, to support Arnot's ideas.

Arnot is careful to point out that although the research in this area is strongly suggestive, it is still inconclusive. Readers are provided the facts in a fair and relatively unbiased manner, for the most part, and can draw whatever conclusions they like. Arnot has certainly provided compelling evidence to support his theories, and the information on prostate cancer alone is worth the price of the book. No doubt, this book will take its place on the shelf in many homes, right beside The Breast Cancer Prevention Diet. (Beth Amos)

From the Publisher

Here is a common-sense and exciting new plan to protect men against prostate cancer. The foods men eat can have a profound influence on whether or not they get clinical prostate cancer. Arnot describes these foods and how we can use them as part of a sensible and delicious eating program. He bases his menus on the cuisines from other cultures where the incidence of prostate cancer is dramatically less than in the U.S. Includes: delicious recipes, advice on eating out, stress-busting techniques, fitness programs, a self-test for assessing your own risk, and other prostate cancer-fighting strategies such as promising new drugs and supplements.

Product Details

• Table of Contents
• Read a Sample Chapter

Table of Contents

Read a Sample Chapter

The Prostate Cancer Protection Plan

Back Bay Books

Chapter One

Men in Japan and China have up to 90 percent less prostate cancer than American men. That's an astounding statistic. Ninety percent! Most men I talk to are at first surprised at the huge disparity. Their second reaction is to sort of shrug and say, "It's in the genes, nothing much you can do about that." But that's where they're wrong. The best evidence points squarely to a difference in nutrition as a much bigger major factor. The evidence is fascinating. Laurence Kolonel, M.D., Ph.D., professor at the University of Hawaii, hit on a brilliant research strategy. Why not study men who migrated from the Far East to the United States and see if their risk of cancer increased? After all, emigrating wouldn't change their genetic makeup. What happened? Bingo! Dr. Kolonel hit the nail on the head. "I would say that the case of migrants is the strongest indication that the environment is influencing prostate cancer risk," he says. He showed that when the Japanese move away from Japan, their rates of prostate cancer do increase. Now most "migrant studies," as they are called, show the greatest increased risk in the children and grandchildren of the migrants. And that's what you'd expect. The first generation would largely maintain their traditional ways, and the younger generations would adapt more readily to the new environment: burgers, fries, pizza, sodas, drive-ins, video games ... you name it! That's precisely what happens with breast cancer rates. Asian women living in Asia have 90 percent less breast cancer than American women. But when Asian women move to America, it's their daughters and granddaughters whose rates of breast cancer close in on those of American women. What's so striking about Dr. Kolonel's studies is this. For men who moved from Japan to Hawaii, Dr. Kolonel found a large increase in prostate cancer rates in the migrants themselves! Say a man emigrates from Japan to Hawaii at age twenty: by the age of fifty, his risk of a clinically significant prostate cancer is much higher than it would have been had he stayed in Japan! Dr. Kolonel found that the risk doubled in these migrants. Here's what he concluded: "Migrants have the same genetic makeup as their families back home, and so it must be something external that is causing the risk change." So, if environment is changing risk, the question becomes what in the environment is affecting risk? Which lifestyle component is raising risk? Suggests Dr. Kolonel: "Diet is a good candidate. When Japanese migrants come to Hawaii, the biggest area of change for them is diet since Hawaii is not a heavily industrialized or polluted state. What changes here is exposure to Western diet."

What is this Western diet? Dr. Kolonel explains that it's a diet heavily based on animal products - particularly meat and dairy products - and therefore higher in fat, especially animal fat, than the diet of more traditional populations in Asia and Africa. As populations become more Westernized, they shift away from whole grains and cereals toward meat and dairy, and this changes the nature of their fat intake to more saturated fats. In comparison to the diets of Africa and Asia, the Western diet contains a lower intake of fruits and vegetables.

Now let's take a closer look at prostate cancer numbers. We read in the introduction that many of us have a latent cancer, even at a fairly young age. You'll recall that even for men in their 30s, 25 percent have latent cancer. Here's the big Latent cancer is not unique to the United States. Researchers find that, at any given age, men all over the world share the same risk for latent cancers. They have the same percentage of latent cancers at the same ages we do. You might be tempted to say: Huh? I thought you said men in other countries, especially the Far East, have less cancer. Well I did. They have less clinical cancer, but not less latent cancer.

Remember, latent cancer is in a quiescent stage that poses no harm. Let's take China as an example. Chinese men have the same percentage of latent cancer as American men. That's right. They have just as much latent cancer as you or I. But hold on! How many of those latent cancers become a clinically important cancer? In China, the answer is extremely few. Clinical rates in China are the lowest in the world at 2.8 per 100,000 people a year. American whites have 100 per 100,000. That's thirty-six times higher than rates in China. So if American and Chinese men start at square one with the same amount of latent cancer, what accounts for the difference in rates of clinical cancer? Why do these latent cancers spring to life in so many American men and not in Chinese men? What is the fuel that transforms a benign, latent tumor into a life-threatening one? In a word, diet. Charles Myers, M.D., of the University of Virginia, also concludes: "Diet definitely affects the progression of prostate cancer from a microscopic level to a metastatic level."

Here's the real irony. Sure, men eating traditional foods in the Far East have low rates of cancer, but what about those men tempted by a change to a Western diet? When they do switch, watch out. Take the burgeoning metropolis of Shanghai, where it's becoming as easy to get a burger, fries, and a shake as it is to get spring rolls and tofu. The rate of clinical prostate cancer is now beginning to rise among those men who have crossed the line from traditional to Western foods. Ann Hsing, Ph.D., epidemiologist at the National Cancer Institute, conducted a study in Shanghai to examine why prostate cancer rates were increasing. She analyzed the diets of men at high risk for prostate cancer. Sure enough. What were they eating? For starters, more animal fats, especially red meat, and preserved foods such as preserved meats and vegetables. With increased animal product intake, more calories were coming from animal fat. Add to that lots more calories than the Chinese traditionally eat. The result: these men weren't just getting prostate cancer, they were also fat. In fact, they developed the most dangerous kind of obesity, called central obesity, which occurs when fat piles up around your midsection. Central obesity is commonly seen in people who eat large amounts of starches, refined flours, and sugars. The good news is that the men who ate healthier traditional foods and vegetables such as garlic, scallions, and onions had a lower risk. The traditional Chinese diet has more fiber, plenty of fruits, and lots of soybeans, green leafy vegetables, and orange vegetables such as pumpkin. In the traditional Chinese diet, 60 percent of energy intake came from complex carbohydrates. "I think our findings corroborate findings in the U.S.," says Dr. Hsing.

How Big a Villain Is the Western Diet?

The Japanese flat-out blame the Western diet for their prostate cancer travails: There were 5,399 deaths from prostate cancer in 1995 in Japan. By 2015 that number will increase to 13,494. Dr. Y. Kakehi of the Department of Urology, Faculty of Medicine, Kyoto University, concludes: "Change in dietary habit (more Western-style diet) is considered to be a major cause of the increase." English researchers too have concluded that nutrition is the major risk factor associated with prostate cancer, singling out low intake of fresh fruit, low intake of vegetables, and low intake of whole-grain cereal, as well as excess body fat.

The Association for the Cure of Cancer of the Prostate (CaP CURE) writes in its white paper on nutrition: "Of all the risk factors for prostate cancer, only nutrition seems to explain the differences in global distribution of this disease." Studies estimate that 75 percent of all cases of prostate cancer could be prevented by changes in diet and lifestyle. Scientists from Cap CURE conclude: "We believe, therefore, that nutrition and lifestyle practices in lower-risk countries arrest the growth of prostate cancer so that it is never clinically discovered."

Okay, you may say, what does all of this high-powered epidemiologic research have to do with me? After reading the thorough research on nutrition and prostate cancer, I have to tell you that I'm convinced. As a physician and as a male concerned about prostate cancer, I believe this research is the strongest indication that diet plays a big role in prostate cancer and that there is something you can do about your own diet to change your risk. This isn't just a pipe dream; this could be close to the whole game. But I asked myself: Which foods? What diet? Well, you're in for a real treat. There is a true treasure trove of terrific foods that can help protect you against prostate cancer. If you're like me, you don't just want to read a lot of wishful thinking by well-meaning advocates of alternative medicine. You want hard facts. The hard facts, in this case, show that foods have highly specific effects on the prostate gland. These are varied enough to give you a range of strategies to protect yourself. You'll also find, as I have, that this is high-level science. Foods have incredibly sophisticated powers, like well-designed pharmaceuticals. Researchers are excited enough about the power of foods that they're already intensely investigating many of them. In fact, tens of millions of dollars are being spent on nutritional research. The next section of the book will present these foods and tease apart their specific actions that can help you protect yourself against prostate cancer. You'll be pleased to learn that virtually all of them have terrific general health benefits, from lowering your cholesterol and your risk of heart disease to controlling your weight and risk of other cancers. They are also foods that will make you feel terrific, perhaps the best you have ever felt. I hope you'll develop the same enthusiasm for the foods and meals in this book that I have. Tens of thousands of men threatened with prostate cancer have already made the change. Most telling of all, men who already have the disease are finding remarkable changes in the state of their cancer with a rigorous change in diet.

Why? The most intriguing reason is that our bodies are designed to eat a specific diet. Just as putting low-grade, cheap gas into a car will eventually ruin a car engine, putting cheap fuels that we were not designed to use into our own bodies will lead to disease. Specifically, the human prostate and the Western diet may be incompatible. You see, through human evolution, our bodies became accustomed to specific foods. Unfortunately, our bodies can't turn on a dime and acclimatize overnight to a new diet, especially one loaded with animal fats and refined carbohydrates, almost devoid of fruits and vegetables. Human evolution marks time in the tens of thousands of years. The dramatic changes in our diets since the Industrial Revolution aren't even a tick on our evolutionary clocks. What's the diet we as men are meant to eat? Is it roast beef with Yorkshire pudding, roasted potatoes, and gravy? Not if you look back into the dawn of humankind.

For 90 percent of the last 200,000 years, we were fruit-and-vegetable eaters. Donald Coffey, Ph.D., who is a professor in the famed Department of Urology at Johns Hopkins, argues that humankind did not evolve fully equipped to be dairy or meat eaters. More to the point, our prostates may not have evolved to handle a diet rich in fats. Humans came from an arm of evolution that did not eat a lot of meat. Until 2.5 million years ago, we were mainly gatherers - we ate seeds and fruits and nuts. Homo sapiens first appeared 100,000 years ago, but only 9,000 years ago did we start processing and storing food and trading it. That's when we started down the road to eating the massive amounts of carbohydrates that we eat today, for example, corn, wheat, rice, barley, potatoes, and root plants. Fruit consumption dropped, since fruits were harder to store. And as we increasingly ate a diet rich in meat, which we cooked and even burned, we stopped eating as many fruits and vegetables. Dairy got big only around 3,000 years ago, and it's then that we increased our dairy intake. Before that we would get milk from goats and sheep, but it was only when we bred these animals that we developed the dairy industry.

"After fifty years of trying to prevent cancer, we've learned that we should go back to eating the foods we ate while we were evolving," says Dr. Coffey. He adds, "It's not surprising that the American Cancer Society and the National Cancer Institute make the same suggestions. They tell us to return to the diet we ate when we were evolving: more vegetables, more fruit, more fiber, less red meat, less animal fat, less dairy, less barbecuing, and more aerobic exercise." So who eats a diet closer to the one we were designed to eat? In parts of China, people eat around 6 to 8 percent fat. Compare that to the United States, where the figure is 30 to 40 percent, much of it animal fat. "Put it all together and you'll figure that our lifestyle is giving us cancer," says Dr. Coffey. I swear the reason I feel so terrific on this diet is that it's the one we're supposed to eat, the one we are designed to eat.

The great good news is that there is a diet that humans were designed to eat and a diet that can be highly protective against prostate cancer. The evidence is so strong that many top physicians in the best academic centers put their patients on a "prostate cancer diet." But don't take my word for it; just look at what the top experts have to say about diet in their own patients with prostate cancer.

Charles Myers, M.D., of UVA, says: "I recommend a diet change as an adjunct to treatment to every patient. I don't recommend a diet change as a sole treatment. However, some men have very slow-growing cancers - their tumors double every four to five years. In that subset a change in diet may be enough." Dr. Myers recommends essentially the same diet that Milken and Ornish recommend.

Erik Goluboff, M.D., of Columbia University, says: "I put all of my patients on a prostate cancer diet." I'm impressed that so many experts believe that diet could have an effect even on men who already have prostate cancer. Even more compelling than the use of a prostate cancer diet in treatment of patients is the growing interest in a prostate cancer diet for prevention.

"Even if you're dealt a bad hand in terms of your prostate cancer genetics, such as faulty male sex hormone receptors, diet may still influence the likelihood of that cancer turning bad," says Christopher Logothetis, M.D., of M. D. Anderson Cancer Center at the University of Texas in Houston.

"Diet will hinder or help mutations that could lead to the development of a tumor," says Linda Nebeling, Ph.D., M.P.H., R.D., nutritionist at the National Cancer Institute.

Continues...

---

Excerpted from The Prostate Cancer Protection Plan by Robert Arnot Copyright © 2000 by Robert Arnot, M.D.. Excerpted by permission.
All rights reserved. No part of this excerpt may be reproduced or reprinted without permission in writing from the publisher.
Excerpts are provided by Dial-A-Book Inc. solely for the personal use of visitors to this web site.

---