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(Hardcover)
There are disorders that defy treatment with prescribed pharmaceuticals: a man’s hands shake so hard that he cannot hold anything; a woman is mired in severe inescapable depression. For these patients and others, an alternative is emerging: deep brain stimulation. In this fascinating and timely investigation, well-known science writer Jamie Talan explains a cutting-edge medical development that is surprising and impressing researchers around the world.
More than 40,000 people worldwide have undergone deep brain stimulation, which involves implanting electrodes in the brain that are connected to a device similar to a pacemaker. With compelling profiles of patients and an introduction to doctors and scientists who are pioneering the research, Talan describes the ways in which deep brain stimulation has produced promising results in the treatment of diseases such as Parkinson’s disease, depression, obsessive-compulsive disorder, and dystonia—as well as the ethical issues that have arisen in the course of this research.
In a unique and cogent treatment of the surgical technique called deep brain stimulation (DBS), award-winning science writer Talan summarizes the history of brain-based medicine beginning in the late 19th century. Better understanding of the mind-body relationship, improved imaging techniques, and advances in surgery make DBS possible today. Surgeons can implant battery-powered electrodes into targeted brain regions of a patient who is awake and responsive. The technique can help people suffering from severe Parkinson's disease, dystonia, obsessive-compulsive disorder, depression, Tourette's syndrome, or epilepsy. Those with chronic pain or minimal consciousness may also benefit. The outcome can be remarkable, but Talan reminds readers that DBS is a complicated procedure requiring the utmost patience and persistence because improvement may not occur or may be delayed. Ideally, a DBS team should consist of a neurosurgeon, a neurologist, a psychiatrist, a psychologist, and an ethicist. Chapter notes and a list of resources provide avenues for further research. An excellent choice for large public, health-oriented, or academic libraries.
More Reviews and RecommendationsScience writer Jamie Talan shared the 1998 Edgar Award with Richard Firstman for best nonfiction for The Death of Innocents, a story of forensic science that was also a New York Times Notable Book of the Year. Talan covered neuroscience for Newsday for more than twenty years and is currently science writer-in-residence at The Feinstein Institute for Medical Research in New York.