Preface vii
Acknowledgments ix
Contributors xi
1 Molecular Biology of Cancer Part 1 Robert A. Kratzke 1
2 Molecular Biology of Cancer Part 2 Sunit Srivatsava George R. Simon 18
3 Etiology of Cancer Part 1 Shirish M. Gadgeel 33
4 Etiology of Cancer Part 2 Nikhil I. Khushalani Kaunteya Reddy 56
5 Epidemiology of Cancer Thomas E. Stinchcombe 69
6 Principles of Surgical Oncology Rebecca L. Aft Jason Keune 76
7 Principles of Radiation Oncology Hak Choy L. Chinsoo Cho 81
8 Principles of Medical Oncology Sujatha Murali Suresh S. Ramalingam 91
9 Principles of Immunotherapy Sara K. Butler 100
10 Principles of Health Services Research Boone W. Goodgame 107
11 Systemic Therapy for Cancer Richard A. Walgren 114
12 Design and Analysis of Clinical Trials Feng Gao Kathryn Trinkaus 128
13 Cancer Prevention Daniel Morgensztern Vorachart Auethavekiat 140
14 Genetic Counseling Jennifer Ivanovich 147
15 Cancer Screening Megan E. Wren 162
16 Advances in Diagnostics Sanjeev Bhalla Cylen Javidan-Nejad 168
17 Cancer of the Head and Neck David I. Kuperman 190
18 Cancer of the Lung Janessa J. Laskin 198
19 Neoplasms of the Mediastinum Gregory P. Kalemkerian 210
20 Cancer of the Gastrointestinal Tract 224
Section 1 Esophagus and Stomach Renuka V. Iyer 224
Section 2 Pancreas Renuka V. Iyer 236
Section 3 Hepatobiliary Renuka V. Iyer 243
Section 4 Small Intestine and Gastrointestinal Stromal Tumors Benjamin R. Tan 249
Section 5 Colorectal and Anal Cancers Benjamin R. Tan 257
21 Genitourinary Cancer Walter M. Stadler 265
22 Cancer of the Testis Daniel Morgensztern 284
23 Gynecologic Cancers 293
Section 1 Ovarian David G. Mutch 293
Section 2 NonovarianMatthew A. Powell 300
24 Cancer of the Breast Kathy D. Miller 317
25 Cancer of the Endocrine System Rami Y. Haddad Mouhammed Amir Habra 336
26 Sarcomas Douglas R. Adkins Becky J. Ganz Toni B. Rachocki 350
27 Benign and Malignant Mesothelioma Maria Q. Baggstrom 359
28 Cancer of the Skin and Melanoma Gerald P. Linette 364
29 Neoplasms of the Central Nervous System Janakiraman Subramanian 371
30 Cancers of Childhood Shalini Shenoy 380
31 Lymphomas Camille N. Abboud 399
32 Acute Leukemias John Welch Amanda F. Cashen 423
33 Chronic Leukemias James C. Mosley III Keith Stockerl-Goldstein 435
34 Plasma Cell Neoplasms Ravi Vij Giridharan Ramsingh 444
35 Paraneoplastic Syndromes C. Daniel Kingsley Michael C. Perry 449
36 Cancer of Unknown Primary Site Sunny Wang Sarita Dubey 456
37 Peritoneal Carcinomatosis Andrea Wang-Gillam David D. Tran 465
38 Immunosuppression-Related Maligancies Lee Ratner 474
39 Oncologic Emergencies Giridharan Ramsingh Daniel Morgensztern 477
40 Treatment of Metastatic Cancer Arkadiusz Z. Dudek 483
41 Stem Cell Transplantation Mark A. Schroeder Peter Westervelt 501
42 Infections in Cancer Patients Alex E. Denes 514
43 Management of Adverse Effects of Treatment Maria Q. Baggstrom 524
44 Supportive Care and Quality of Life Anna Roshal 532
45 Rehabilitation of the Cancer Patient Janakiraman Subramanian 546
46 Societal Issues in Oncology Thomas H. Fong 551
47 Information Systems in Oncology Howard L. West 558
48 Complementary, Alternative, and Integrative Therapies in Cancer Care Vamsidhar Velcheti 566
49 New Approaches in Cancer Treatment Nithya Ramnath Anubha Bharthuar Krishnan Raghavendran 572