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$174.95

Textbook Details

  • EDITION:
    1st Edition
  • ISBN:
    1420068814
  • ISBN-13:
    9781420068818
  • PUB. DATE:
    October 2009
  • PUBLISHER:
    CRC Press
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Autism: Oxidative Stress, Inflammation, and Immune Abnormalities / Edition 1 by Abha Chauhan, Ted Brown, Ved Chauhan

$174.95 List Price
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Autism

Product Details

  • Pub. Date: October 2009
  • Publisher: CRC Press
  • Sales Rank: 414,689

Synopsis

In 2007, the Centers for Disease Control and Prevention issued an autism alarm estimaring that one in l50 children may be affected by autisiiL-spectrum disorder. Autism has been treated mainly with technical approaches: principally applied behaviour analysis and psychopharmacology. The findings in this book Implicate oxidatives stress as a common feature in autism and, support the claim in oxidative stress and intracellular redox imbalance can be induced or triggered in autism by exposure to certain environmental agents. Such findings could point the way to new treatment approaches in autism.

Autism: Oxidative Stress, Inflammation, ami Immune Abnormalities brings together a wealth of cutting-edge evidence that is already influencing how we treat this serious condition. It looks at the role of neuropathologies abnormalities, generics, and those factors common to oxidative stress such as inflanunation, immune dysfunction, aberrant cellular signaling, and gene-environment interactions. Among dozens of research topics, this volume-

Looks at interactions between genetic and environmental factors such as the maternal immune environment and prenatal/postnatal environmental stressors

Summarizes evidence for oxidative damage and inflammation in autism

Introduces a PDD behavior inventory as a tool for assessing autism

Considers autism as an aberrant adaptive response to neuroinflarnmation and oxidative stress

Examines the role of abnormal calcium signaling and the hypothesis that it may represent a target for novel therapeutics

Presents a hypothesis that autism arises from the dysregulation of a unified gut/brain system rather than originating in the brainalone

Proposes the utility of using a biopsychosocial method to treat autism

This book shows us that autism is not only developmental but also a chronic condition based on active pathophysiology, and that it is not only behavioral but also ptesents somatic and systemic features. The findings in these chapters support the theory that oxidative stress plays an important role in autism. They also point to the value of conducting in-depth mechanistic studies as a way to uncover new targets for therapeutic intervention in autism.